Variation in natural selection: there’s more to it than randomness

Important take-home lessons from the molecular studies are: Hereditary change is an active cell process rather than a passive series of accidents; Hereditary changes affecting the whole genome can happen rapidly; Biochemical processes that generate genetic and epigenetic variation are subject to control and targeting within the genome by cell regulatory networks; and Cell change activities reflect the life-history experience of the organism and thus provide the basis for ecological feedback into evolutionary variation.


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